From 5 to 7 June 2024 took place in Würzburg (Germany) the 1st International Conference of the Würzburg Initiative 3R (WI3R).
The Würzburg 3R Initiative bundles Bavarian 3R activities from academia, regulatory authorities and industry and networks with existing 3R centres in Germany, Europe and worldwide. The conference provided a platform for discussion and exchange between research and industry on biofabrication and 3D printing, human iPSC and organoids, emerging technologies, NAMs, disease modelling, and regulatory acceptance. About 200 people, mainly from research and scientific community joint the event!
With the title “Dynamic in vitro and ex vivo models on-a-chip: Bridging the gap between high throughput screening and systemic studies in vivo”, Sylvia Wagner, from Fraunhofer IBMT, presented her work in SSbD4CheM on a poster presentation. A fluidic system approach was presented which is suitable for various fields of application: (a) Mucus barrier simulation for testing the permeation of drugs and chemicals (b) Cultivation of 3D cell cultures under dynamic flow (c) Dynamic cultivation of 2D cell cultures (d) Combination of mucus model, 2D model and/or 3D models (e) Combination with inline analysis of the cells (live imaging, electrical measurements, sensor technology). This conceptual approach is implemented, optimised and applied in the SSbD4CheM project. During the event, our colleague was able to establish new industrial contacts and introduced the SSbD4CheM project to them regarding potential exploitation concepts.
